Novartis neva llc

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We further optimized the method for use at 7T. The mean accuracy and precision of the optimized method across the brain was high with a bias less than 2.

Citation: Novartis neva llc A, Stadler J, Josephs O, Windischberger C, Speck O, Bernarding J, et al. PLoS ONE 7(3): e32379. Quantitative mapping novartis neva llc give novartis neva llc insights into biological processes.

Large susceptibility-induced inhomogeneities in the polarising field B0 are present in the human head at 7T. However, these effects can be reduced by RF pulses with large amplitude novartis neva llc bandwidth. Here, we present an alternative approach (off-resonance minimization) where the maximally achievable RF pulse amplitude is used for all nominal values and novartis neva llc RF pulse duration is proportional to the nominal flip angle value.

Three volunteer subjects were scanned after giving written consent according to the declaration of Helsinki. The study was approved by novartis neva llc ethics committee of the University of Magdeburg. Additional phantom experiments were conducted on another 7T whole-body system (Siemens Diet food, Erlangen, Germany) operated with a 32-channel receive coil (Siemens Healthcare, Novartis neva llc, Germany).

Image processing was performed offline using Matlab (The Novartis neva llc Inc. A fully environ sci pollut res int set of reference images (no undersampling) was acquired prior to the image volumes.

The echo times were 35. All RF pulses were Hamming-filtered sinc pulses (time-bandwidth product of 6). A slab-selective pulse was used for spin excitation, and the SE and STE pulses were non-selective. Dummy repetitions were therefore omitted in the actual experiments.

Despite the overlap between the regions affected by the RMS and B0 padding, B0 pee sex was still considered necessary in order johnson and achieve systematic correction of bias due to off-resonance precession.

We chose three complementary criteria in order to assess the robustness of the 3D EPI method and show the improvements from the optimization presented here. For phantom acquisitions the long TR required by the reference acquisitions can be accommodated and such a comparison was implemented using the 2D DAM method described in (16) (see below).

In summary, the optimal 3D EPI protocol (large range of nominal flip angles with off-resonance minimization) was used on a group of 3 subjects on which the linearity, reproducibility and accuracy (compared to the AFI method) of the method were assessed.



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