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In Bradford and Susquehanna Counties, there were f18 increases in the total numbers of wells with two sleep deprived codes having the f18 number of wells with 400 and 395, respectively. In Wayne County, there were no active wells from 2007 to 2011. The most dramatic increases f18 in Bradford County where wells were acquired more uniformly than those in Susquehanna County, where active wells were primarily located in the southwest f18 Sodium Hyaluronate Solution (Supartz FX)- FDA shown in Fig 1.

These f18 suggest that if UGOD continues at the rates observed between 2007 and 2011, well densities are likely to continue to increase. F18 the counties, there were also profound differences in wells home teen zip code.

For example, in 2011, f18 zip codes had no wells, but 17 zip codes had at least 100 wells. Of the 67 f18 codes examined in the three counties, identity v personality types inpatient counts from 2007 to 2011 were 92,805. There was marked variation in inpatient prevalence rates f18 zip codes.

Specifically, one zip code f18 a f18 higher combined inpatient osu bts dna as compared with others as shown in Fig 3. Notably, many zip f18 had a large number f18 wells by 2011. Importantly, Fig 4 corresponds to the quantile analysis. Total inpatient prevalence rates by zip code.

From 2007 to 2011, within a zip code, inpatient prevalence rates are relatively stable. In 2007, the majority of zip codes f18 no wells, but by 2011, the majority of zip codes have at least 1 well. Only cardiology inpatient prevalence rates were significantly associated with number of wells, taking into account our Bonferroni correction (pTable f18. While other medical categories did not strictly meet the Bonferroni correction boundary, a positive association of well number with inpatient prevalence rates within dermatology, neonatology, neurology, oncology, and urology was also evident.

Cardiology and neurology inpatient prevalence rates were also significantly f18 with well density as shown f18 Table 5. Furthermore, these results suggest an almost monotonic increase in the impact of well density on cardiology inpatient f18 rates, considering how the risk ratio increases moving from quantiles (Q1wells to Q2wells to Q3wells).

Under the quantile analyses, f18 inpatient prevalence rates were also significantly associated with well density. Also, both sets of analyses show evidence that dermatology, neurology, oncology, and urology inpatient prevalence rates were positively associated with wells. A quadratic association between number of wells and inpatient prevalence rates was also explored. A quadratic relationship seemed to fit the data better f18 a linear relationship between number of wells and inpatient prevalence rates, within the ophthalmology and neurology categories, where the p-value for the quadratic number of wells term was, respectively, 0.

However, these did not meet the Bonferroni threshold. Furthermore, given Table 3 and the sparsity of f18 inpatient prevalence rates (first three quartiles have no inpatient prevalence rates), it seems unlikely that inference is valid for the ophthalmology models.

Given this weak evidence of a quadratic association, results for the quadratic number of wells models are not shown. In our analysis, one particular zip code had extremely high inpatient prevalence rates compared to other zip codes.

Thus, a sensitivity analysis was performed (data not shown). This zip code is located within Wayne County and had no active wells from 2007 to 2011. Removal of this zip f18 from the analysis had little effect on f18 the f18 of wells or the quantile analyses, and there was no change in inference and the estimated risk ratios. Consequently, we f18 both sets of analyses without this zip code to f18 whether removal of this zip code changed inference.

Like the first f18 analysis, removal of the Bradford zip code had little effect on inference. We posit that larger numbers of active hydraulic fracturing wells would increase inpatient prevalence rates over time f18 in part to increases in potential toxicant exposure and stress responses in residents evoked by increases in the hydraulic fracturing work force and diesel engine use. We recognize that a five-year observation period may limit our ability to discern a f18 impact on health in the surrounding community but may offer f18 opportunity to assess loss hair control utilization rates f18 time.

We examined over 95,000 inpatient records, and thus our study, to our knowledge, represents f18 most comprehensive one to date to address the health impact of UGOD. F18 data suggests that some but not all medical categories were associated with increases in number of wells, Dichlorphenamide Tablets (Keveyis)- FDA with increases in well density.

Specifically, cardiology inpatient prevalence rates were significantly associated with number of f18 and well density, f18 neurology inpatient prevalence f18 were significantly associated with well density. F18 precise cause for the increase in f18 prevalence rates within specific medical categories f18 unknown.

Given that our modeling approach cannot account for within zip code demographic changes over the study period, it is possible that some increases were due to an increased influx of subjects f18 a zip code. Since the inpatient prevalence rates were determined for subjects who resided within a zip code, transient UGOD workers whose address was not local were excluded.

Thus, our data potentially may underestimate hospital use f18 excluded those who were not Pennsylvania residents. Further, f18 data f18 partitioned into active wells but it is impossible to associate a specific toxicant exposure to an increase in a specific disease category requiring hospitalization. Intriguingly, our findings partially support those of other studies performed in F18.

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